Innovative Therapy • Prescription Required
Low-Dose Naltrexone (LDN) Compounding
Customized Low-Dose Naltrexone (LDN) formulations prepared at Rock Ridge Pharmacy in Glen Rock, NJ. Tailored dosing and delivery options designed to support patients with autoimmune conditions, chronic pain, and prescriber-directed integrative treatment protocols.
What Is Low-Dose Naltrexone (LDN)?
Low-Dose Naltrexone (LDN) is a compounded therapy that uses very low doses of the medication naltrexone (typically 1–5 mg) to modulate the immune system, reduce inflammation, and support patients with chronic health conditions.
LDN is being studied for its potential role in autoimmune disorders, fibromyalgia, chronic pain, multiple sclerosis, and neurological conditions. Each prescription is carefully customized at Rock Ridge Pharmacy in Glen Rock, NJ.
How Does Low-Dose Naltrexone (LDN) Work?
Endorphin Release
Increases secretion of endorphins for natural pain relief and well-being.
Opioid Growth Factor (OGF)
Stimulates OGF release, reducing inflammation and modulating immune response.
Immune Modulation
Reduces inflammatory immune signaling via Toll-like Receptor-4 pathways.
Glial Cell Regulation
Calms glial cells to reduce nerve inflammation and protect neurons.
Dopamine Increase
Boosts dopamine levels for improved mood, energy, and cognition.
Benefits of Low-Dose Naltrexone (LDN)
Autoimmune Support
Helps regulate immune system activity in conditions such as MS, Crohn’s, Hashimoto’s, lupus, and rheumatoid arthritis.
Chronic Pain Relief
May improve symptoms of fibromyalgia, CRPS, neuropathic pain, and other persistent pain conditions.
Neurological Health
Studied in Parkinson’s, Alzheimer’s, multiple sclerosis, and restless leg syndrome for potential neuroprotective benefits.
Inflammation Control
Helps reduce systemic and gut inflammation in IBS, ulcerative colitis, celiac disease, and related conditions.
Dermatology Uses
Sometimes prescribed for psoriasis, eczema, and other chronic inflammatory skin conditions.
Ongoing Research
Investigated for cancer, HIV/AIDS, Lyme disease, autism spectrum disorders, traumatic brain injury, and weight management protocols.
How to Start Low-Dose Naltrexone (LDN)
A step-by-step guide to safe titration and dosing, personalized to your health needs.
Step 1: Start Low
Begin with 1.5 mg daily for 1–2 weeks to allow your body to adjust gradually.
Step 2: Increase Gradually
Raise the dose by 0.5 mg every 1–2 weeks, monitoring benefits and any side effects.
Step 3: Target Dose
Most patients reach 3–4.5 mg daily, adjusted to individual response and tolerance.
Explore Our Low-Dose Naltrexone (LDN) Dosage Forms
At Rock Ridge Pharmacy, we provide a comprehensive selection of Low-Dose Naltrexone (LDN) dosage forms. Whether you prefer capsules, liquid suspensions, topical creams, troches, or titration kits, we have the right solution for your needs.
Supplements to Support LDN Therapy
When using Low-Dose Naltrexone (LDN) , certain supplements may improve tolerance, reduce side effects, and support immune balance.
- Omega-3 Fatty Acids – support anti-inflammatory balance
- Vitamin D₃ – helps regulate immune function
- Magnesium Glycinate – promotes relaxation and sleep
- Probiotics – support gut health and balanced immunity
- Alpha-Lipoic Acid (ALA) – antioxidant for nerve protection
Note: These supplements are supportive and not a replacement for LDN. Always consult your provider or pharmacist before starting new supplements.
Storage & Safety Information for Low-Dose Naltrexone (LDN)
Proper handling and monitoring of compounded LDN ensures its effectiveness and patient safety.
Storage Guidelines
Store compounded LDN capsules at 68°F–77°F (20°C–25°C) in a cool, dry place away from heat, humidity, and direct sunlight. Do not refrigerate or freeze unless instructed. Always keep LDN in its original container.
Store out of reach of children and pets. If appearance or odor changes, contact your pharmacist before use.
Questions? Call (201) 444-4190 or email info@rockridgepharmacy.com .
Safety & Possible Side Effects
Common side effects include vivid dreams, mild headaches, or temporary stomach upset. Short-term effects like occasional insomnia or fatigue usually resolve in a few days. Rare reactions such as mood changes or dizziness are uncommon and often dose-related.
Disclaimer: This information is for educational purposes only and not a substitute for medical advice. Always consult your healthcare provider before starting, changing, or discontinuing compounded LDN therapy.
How Quickly Does Low-Dose Naltrexone (LDN) Work?
The onset of benefits depends on the condition being treated and individual patient response.
Autoimmune & Pain Conditions
For conditions like fibromyalgia, MS, or chronic pain, patients may notice improvements within 2–6 weeks, though steady benefits often build over several months.
Neurological & Mood Support
In cases of depression, PTSD, or neurological conditions, benefits may take several weeks to months, with gradual improvements as endorphin levels stabilize.
Key Takeaway
LDN works gradually and consistently. Close monitoring and open communication with your provider ensure dosing adjustments and the best long-term results.
Cost of Low-Dose Naltrexone (LDN)
Custom Compounding: LDN is prepared in personalized doses not available commercially, ensuring therapy tailored to your specific needs.
Affordable Pricing: Rock Ridge Pharmacy offers competitive pricing options, keeping LDN therapy accessible while maintaining the highest compounding standards.
Expert Guidance: Every prescription is compounded with precision and oversight from our pharmacists, who also provide ongoing support for dose adjustments, safety, and long-term use.
For details on custom LDN pricing, please call Rock Ridge Pharmacy at (201) 444-4190 or email info@rockridgepharmacy.com .
Is Low-Dose Naltrexone (LDN) Right for You?
Key considerations when evaluating whether LDN therapy may support your health needs.
Assess Your Condition
LDN is commonly used off-label for autoimmune conditions (MS, Crohn’s, Hashimoto's), chronic pain (fibromyalgia), and neurological disorders (Parkinson’s, Alzheimer’s). If you live with one of these, LDN may be worth exploring.
Consider Individual Variability
The effectiveness of LDN differs for each person. Factors such as overall health, severity of condition, and prior treatment responses influence results.
Monitor & Adjust Your Dose
LDN is usually started at 1.5 mg daily and increased gradually. Tracking symptoms and side effects helps find the optimal dose tailored to you.
Feedback & Risks
Stay in close contact with your healthcare provider to adjust treatment and monitor side effects. LDN is generally well-tolerated, with minor effects like vivid dreams or headaches balanced against potential benefits.
Disclaimer: This content is for educational purposes only and does not replace professional medical advice. Always consult your healthcare provider before starting or adjusting LDN therapy.
Why Rock Ridge Pharmacy for Compounded LDN?
- Personalized doses — available in 0.5 mg to 4.5 mg, tailored to your provider’s prescription.
- USP <795> & <800> compliant lab — ensuring purity, safety, and accuracy.
- Fast turnaround — most prescriptions ready within 24–48 hours in New Jersey.
Our compounding pharmacists carefully prepare each prescription of Low-Dose Naltrexone, following strict quality standards and reviewing every formulation to align with your provider’s treatment plan.
Patients also receive personalized pharmacist support — from dosing guidance to monitoring side effects — ensuring LDN therapy is both safe and effective for long-term care.
Low-Dose Naltrexone (LDN) FAQs
Find answers to the most common questions about compounded Low-Dose Naltrexone at Rock Ridge Pharmacy.
What is Low-Dose Naltrexone (LDN) and how is it compounded at Rock Ridge Pharmacy?
LDN is a customized medication made in doses of 0.5–4.5 mg, compounded by our pharmacists in Glen Rock, NJ. We prepare capsules, liquids, creams, troches, and other forms tailored to your provider’s prescription.
How does LDN help with autoimmune disorders and chronic pain?
LDN temporarily blocks opioid receptors, boosting endorphins and modulating the immune system. This helps reduce inflammation and pain in conditions like Crohn’s, lupus, MS, and fibromyalgia.
How quickly does LDN start working, and when will I notice results?
Some patients report improvements within 2–6 weeks, though maximum benefits may take several months of consistent use.
What dosage forms of LDN are available at Rock Ridge Pharmacy?
We offer capsules, oral liquids, topical creams, troches, suppositories, lozenges, vaginal creams, and titration kits.
Do I need a prescription for LDN?
Yes. LDN is a compounded medication that requires a prescription from your licensed provider.
How much does Low-Dose Naltrexone cost?
Pricing varies depending on the form and strength. Most insurance plans do not cover LDN, but Rock Ridge Pharmacy offers affordable self-pay options.
Is LDN safe for long-term use?
Yes, when monitored by your healthcare provider. Long-term use is considered safe, with ongoing studies supporting its role in chronic conditions.
Can LDN be taken alongside my current medications?
LDN should not be combined with opioids, but is generally safe with most other therapies. Always review your medications with your provider or pharmacist.
What are the most common side effects of LDN?
Mild side effects may include vivid dreams, temporary insomnia, or headaches. These usually resolve as your body adjusts.
How do Rock Ridge Pharmacy pharmacists support patients on LDN therapy?
Our pharmacists provide one-on-one counseling, answer dosing questions, monitor side effects, and work closely with your prescriber to optimize therapy.
Where can I learn more about LDN research?
Visit the LDN Research Trust or ask our pharmacists for educational resources.
Ways to Send In Prescriptions for Low Dose Naltrexone (LDN)
1. Fax
Write a prescription on a prescription pad and fax over to 201-444-2698
We'll take care of the rest!
2. E-Scribe
E-Rx (E-scribe) to “Rock Ridge Pharmacy”
Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.
3. Call
- Call in your prescription to
- 201-444-4190.
We want to make sure it's as easy as possible for our patients!
4. Telemedicine
Rock Ridge Pharmacy, in partnership with Physician 360, offers convenient on-demand telemedicine consultations for DMSA detoxification and other conditions.
