Customized Therapy • Prescription Required
Low-Dose Naltrexone (LDN) Capsules
At Rock Ridge Pharmacy, we specialize in personalized compounding of Low-Dose Naltrexone (LDN) to support patients managing autoimmune, inflammatory, and chronic conditions.
Low-Dose Naltrexone (LDN) Capsules
Low-Dose Naltrexone (LDN) capsules are a specialized formulation of naltrexone, compounded in very low doses (typically 1.5 mg to 4.5 mg) compared to traditional high-dose use for opioid or alcohol dependence.
Unlike higher doses that block opioid receptors, LDN works by modulating the immune system, reducing inflammation, and supporting management of chronic health conditions such as autoimmune disorders, fibromyalgia, and chronic pain.
Every capsule at Rock Ridge Pharmacy is prepared in our USP <795> / <800> compliant compounding lab to ensure quality, safety, and individualized dosing tailored to your prescriber’s direction.
How Does Low-Dose Naltrexone (LDN) Capsules Work?
Temporary Receptor Blockade
LDN briefly blocks opioid receptors in the brain, initiating a natural rebound effect that enhances healing processes.
Endorphin Production
The temporary blockade stimulates increased endorphin release — natural chemicals that help reduce pain and inflammation.
Immune System Modulation
By boosting endorphins and regulating inflammatory pathways, LDN modulates immune response, making it beneficial for conditions like multiple sclerosis, fibromyalgia, and Crohn’s disease.
Conditions That Can Be Managed with Low-Dose Naltrexone (LDN) Capsules
Autoimmune Diseases
LDN has been used to support patients with multiple sclerosis, rheumatoid arthritis, and lupus by balancing immune system activity.
Chronic Pain Syndromes
May help reduce symptoms of fibromyalgia and complex regional pain syndrome (CRPS) through endorphin regulation and immune modulation.
Inflammatory Conditions
LDN has shown promise in managing gut-related inflammation in Crohn’s disease and ulcerative colitis.
Neurological Disorders
Being researched for conditions such as Parkinson’s disease and chronic fatigue syndrome (CFS/ME) for their neurological and inflammatory components.
How to Start Low-Dose Naltrexone (LDN)
A step-by-step guide to safe titration and dosing, personalized to your health needs.
Step 1: Start Low
Begin with 1.5 mg daily for 1–2 weeks to allow your body to adjust gradually.
Step 2: Increase Gradually
Raise the dose by 0.5 mg every 1–2 weeks, monitoring benefits and any side effects.
Step 3: Target Dose
Most patients reach 3–4.5 mg daily, adjusted to individual response and tolerance.
Supplements to Support LDN Therapy
When using Low-Dose Naltrexone (LDN) , certain supplements may improve tolerance, reduce side effects, and support immune balance.
- Omega-3 Fatty Acids – support anti-inflammatory balance and immune modulation
- Vitamin D₃ – helps regulate immune function and may enhance LDN’s benefits
- Magnesium Glycinate – promotes relaxation, sleep quality, and muscle comfort
- Probiotics – support gut health and balanced immune response
- Alpha-Lipoic Acid (ALA) – antioxidant that supports nerve health and reduces oxidative stress
Note: These supplements are supportive and not a replacement for LDN. Always consult your provider or pharmacist before starting new supplements.
Storage & Safety Information for Low-Dose Naltrexone (LDN)
Proper handling and monitoring of compounded LDN ensures its effectiveness and patient safety.
Storage Guidelines
Store compounded LDN capsules at 68°F–77°F (20°C–25°C) in a cool, dry place away from heat, humidity, and direct sunlight. Do not refrigerate or freeze unless instructed by your pharmacist. Always keep LDN in its original, labeled container.
For safety, store out of reach of children and pets. If you notice any changes in appearance or odor, contact your pharmacist before use.
Questions about storage, expiration, or handling? Call (201) 444-4190 or email info@rockridgepharmacy.com.
Safety & Possible Side Effects
While generally well-tolerated, some patients may experience mild side effects, including:
- Vivid Dreams: Often manageable by adjusting dose or time of administration.
- Sleep Disturbances: Typically temporary and improved with dose adjustments.
- Headaches: Usually alleviated by reducing the dose.
Is LDN Safe for Long-Term Use?
Yes. LDN capsules are safe for long-term use. Ongoing monitoring by a healthcare provider is recommended to ensure effective dosing and adjustments as needed.
How Long Does It Take to See Results?
Most patients notice improvements within a few weeks, but full benefits may take 8 to 12 weeks, depending on the condition and individual response.
Disclaimer: This content is for educational purposes only and is not a substitute for medical advice. Always consult your healthcare provider before starting, changing, or discontinuing compounded LDN therapy.
How Quickly Does Low-Dose Naltrexone (LDN) Work?
The onset of benefits depends on the condition being treated and individual patient response.
Autoimmune & Pain Conditions
For conditions like fibromyalgia, MS, or chronic pain, patients may notice improvements within 2–6 weeks, though steady benefits often build over several months.
Neurological & Mood Support
In cases of depression, PTSD, or neurological conditions, benefits may take several weeks to months, with gradual improvements as endorphin levels stabilize.
Key Takeaway
LDN works gradually and consistently. Close monitoring and open communication with your provider ensure dosing adjustments and the best long-term results.
Cost of Low-Dose Naltrexone (LDN) Capsules
Custom Compounding: LDN is prepared in personalized doses not available commercially, ensuring therapy tailored to your specific needs.
Affordable Pricing: Rock Ridge Pharmacy offers competitive pricing options, keeping LDN therapy accessible while maintaining the highest compounding standards.
Expert Guidance: Every prescription is compounded with precision and oversight from our pharmacists, who also provide ongoing support for dose adjustments, safety, and long-term use.
For details on custom LDN pricing, please call Rock Ridge Pharmacy at (201) 444-4190 or email info@rockridgepharmacy.com .
Is Low-Dose Naltrexone (LDN) Right for You?
Key considerations when evaluating whether LDN therapy may support your health needs.
Assess Your Condition
LDN is commonly used off-label for autoimmune conditions (MS, Crohn’s, Hashimoto's), chronic pain (fibromyalgia), and neurological disorders (Parkinson’s, Alzheimer’s). If you live with one of these, LDN may be worth exploring.
Consider Individual Variability
The effectiveness of LDN differs for each person. Factors such as overall health, severity of condition, and prior treatment responses influence results.
Monitor & Adjust Your Dose
LDN is usually started at 1.5 mg daily and increased gradually. Tracking symptoms and side effects helps find the optimal dose tailored to you.
Feedback & Risks
Stay in close contact with your healthcare provider to adjust treatment and monitor side effects. LDN is generally well-tolerated, with minor effects like vivid dreams or headaches balanced against potential benefits.
Disclaimer: This content is for educational purposes only and does not replace professional medical advice. Always consult your healthcare provider before starting or adjusting LDN therapy.
Why Rock Ridge Pharmacy for Compounded LDN Capsules?
- Personalized doses — available in 0.5 mg to 4.5 mg, tailored to your provider’s prescription.
- USP <795> & <800> compliant lab — ensuring purity, safety, and accuracy.
- Fast turnaround — most prescriptions ready within 24–48 hours in New Jersey.
Our compounding pharmacists carefully prepare each prescription of Low-Dose Naltrexone, following strict quality standards and reviewing every formulation to align with your provider’s treatment plan.
Patients also receive personalized pharmacist support — from dosing guidance to monitoring side effects — ensuring LDN therapy is both safe and effective for long-term care.
FAQs about Low-Dose Naltrexone (LDN) Capsules
What is Low-Dose Naltrexone (LDN) and how is it compounded at Rock Ridge Pharmacy?
LDN is a customized medication made in doses of 0.5–4.5 mg, compounded by our pharmacists in Glen Rock, NJ. We prepare capsules, liquids, creams, and other forms tailored to your provider’s prescription.
How does LDN help with autoimmune disorders and chronic pain?
LDN temporarily blocks opioid receptors, increasing endorphins and modulating the immune system. This may reduce inflammation and pain in conditions like Crohn’s, lupus, MS, and fibromyalgia.
What conditions can LDN support, and who might be a good candidate?
LDN is used off-label for autoimmune diseases, chronic pain syndromes, thyroid conditions, and neurological disorders. Your provider will determine if it is appropriate for you.
How quickly does LDN start working, and when will I notice results?
Some patients report improvements within 2–6 weeks, though maximum benefits may take several months of consistent use.
What dosage forms of LDN are available at Rock Ridge Pharmacy?
We offer capsules, oral liquids, topical creams, troches, suppositories, and titration kits to meet patient and provider needs.
How do you start Low-Dose Naltrexone therapy safely?
Most patients begin at 1.5 mg daily and increase gradually under provider guidance. Our pharmacists support you through titration and dose adjustments.
Can LDN be taken alongside my current medications?
LDN should not be used with opioids, but it is generally safe with most other therapies. Always review your medications with your provider or pharmacist.
What are the most common side effects of LDN, and how can they be managed?
Mild side effects may include vivid dreams, temporary insomnia, or headaches. These usually resolve as your body adjusts.
Is LDN safe for long-term use?
Yes, when monitored by your provider. Long-term use is considered safe, with ongoing studies supporting its role in chronic conditions.
How is LDN different from standard naltrexone doses?
Standard doses (50 mg) are used for addiction treatment. LDN uses 0.5–4.5 mg to target immune modulation, inflammation, and pain control.
Do I need a prescription for LDN at Rock Ridge Pharmacy?
Yes. LDN is a compounded medication that requires a prescription from your licensed provider.
How much does Low-Dose Naltrexone cost, and is it covered by insurance?
Prices vary depending on dosage form and strength. Most insurance plans do not cover LDN, but Rock Ridge Pharmacy offers affordable pricing and guidance.
Can LDN be compounded into topical creams, liquids, or capsules?
Yes, we offer multiple dosage forms to suit patient needs and provider recommendations.
How do Rock Ridge Pharmacy pharmacists support patients on LDN therapy?
Our pharmacists provide personalized counseling, answer questions, and work closely with your prescriber to optimize therapy.
Where can I learn more about LDN research and evidence-based benefits?
You can visit the LDN Research Trust or ask our pharmacists for educational resources.
Get Started with Low-Dose Naltrexone (LDN) Capsules Today!
If you believe LDN capsules may benefit your condition, consult your healthcare provider. Contact Rock Ridge Pharmacy to learn more about our customized compounding services or to start your LDN therapy today.