Ketotifen and Cromolyn
Compounded Ketotifen & Cromolyn Sodium – Mast Cell Stabilizers for MCAS & Mastocytosis
Customized Care • Prescription Required
Ketotifen & Cromolyn Compounding
Personalized mast cell stabilization and allergy support from Rock Ridge Pharmacy in Glen Rock, NJ. Customized formulations of Ketotifen and Cromolyn to reduce inflammation, improve tolerance, and meet individual prescriber and patient needs.
Understanding Mast Cell Disorders
Mast cells are immune cells found in the skin, gut, lungs, and connective tissues that release histamine, prostaglandins, and leukotrienes. In conditions such as Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT), these cells become overactive, leading to symptoms like flushing, hives, digestive upset, breathing difficulties, brain fog, and even anaphylaxis.
At Rock Ridge Pharmacy, we compound Ketotifen and Cromolyn Sodium, two medications that stabilize mast cells and reduce the release of inflammatory mediators. Compounded formulations allow for personalized strengths and delivery forms, improving tolerability and convenience for patients.
Our mast cell–stabilizing therapies help provide symptom relief and improved quality of life for patients in Bergen County and throughout New Jersey.
Compounded Ketotifen & Cromolyn for Mast Cell Disorders
MCAS
Mast Cell Activation Syndrome occurs when mast cells release excess mediators.
Symptoms may include flushing, hives, abdominal pain, or fatigue.
Management often combines trigger avoidance, antihistamines, and stabilizers such as Ketotifen or Cromolyn.
Mastocytosis
Mastocytosis results from increased mast cells in skin, bone marrow, or organs.
Patients may develop rashes, GI upset, or systemic flares.
Compounded Ketotifen and Cromolyn are available in capsules or alcohol-free liquids for improved tolerability.
HAT
Hereditary Alpha Tryptasemia is caused by extra copies of the tryptase gene.
Elevated levels can lead to allergy-like symptoms, joint issues, and connective tissue problems.
Management focuses on lifestyle strategies plus compounded mast cell stabilizers for relief.
What Are Ketotifen & Cromolyn Sodium?
Ketotifen and Cromolyn Sodium are mast cell stabilizers widely used in treating Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT). These conditions occur when mast cells become overactive, releasing excessive inflammatory mediators.
By stabilizing mast cells, these therapies help prevent the release of histamine, prostaglandins, and leukotrienes — compounds responsible for allergic reactions, inflammation, and systemic symptoms.
- Ketotifen – dual-action: stabilizes mast cells and blocks H₁ histamine receptors, providing both prevention and symptom relief. May cause mild sedation in some patients.
- Cromolyn Sodium – pure mast cell stabilizer, non-sedating, and safe for long-term daily use.
At Rock Ridge Pharmacy, we compound Ketotifen and Cromolyn into capsules, suspensions, and liquid solutions to meet individual dosing needs and improve tolerability for patients across New Jersey.
Compounded Ketotifen vs. Cromolyn Sodium
| Category | Compounded Ketotifen | Compounded Cromolyn Sodium |
|---|---|---|
| Pharmacologic Action | Mast cell stabilizer + H₁ antihistamine | Non-sedating mast cell stabilizer |
| Primary Uses | MCAS, mastocytosis, allergic skin/respiratory symptoms | MCAS, mastocytosis, allergic GI disorders, asthma |
| Unique Benefit | H₁ blockade for added relief (itching, hives, swelling) | Minimal systemic absorption; well-tolerated long-term |
| Dosage Forms |
Capsules 0.5 mg1 mg2 mg
Alcohol-free liquid (custom strengths available) |
Capsules 100 mg200 mg
Trigger-free liquid (custom strengths available) |
Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and allergic conditions. Since it is not commercially available in the U.S., compounding ensures patients receive safe, customized therapy tailored to their needs.
Provides custom strengths, filler-free options, and formulations not otherwise available in the U.S.
Key Benefits
- Blocks H₁ histamine receptors to ease allergy symptoms
- Stabilizes mast cells to reduce mediator release
- Helps control itching, hives, swelling, and inflammation
- Suitable for sensitive patients, including excipient allergies
- Supports systemic & gastrointestinal mast cell disorders
Dosage Forms
- Capsules – Custom strengths 0.5 mg, 1 mg, 2 mg
- Alcohol-Free Liquid – Ideal for children, adults with swallowing difficulties, or those sensitive to additives
How Ketotifen Works
Ketotifen stabilizes mast cell membranes, preventing degranulation and reducing the release of histamine and leukotrienes. By blocking H₁ receptors, it decreases allergic responses and improves symptom control. Personalized compounding ensures accurate dosing and better tolerability for long-term mast cell disorder management.
Cromolyn Sodium is a non-sedating mast cell stabilizer commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and allergic gastrointestinal disorders. Because oral forms are not commercially available in the U.S., Rock Ridge Pharmacy compounds Cromolyn into safe, customized therapies tailored to each patient.
Provides capsule and liquid options not sold commercially, with custom strengths, alcohol-free liquids, and additive-free formulations for sensitive patients.
Key Benefits
- Non-sedating, supports clear mental function
- Helps control allergic and inflammatory symptoms
- Safe for long-term use with minimal systemic absorption
- Effective for both systemic and gastrointestinal mast cell disorders
Dosage Forms
- Capsules – Common strengths 100 mg, 200 mg, with additional strengths available
- Trigger-Free Liquid – Alcohol-free, additive-free, ideal for children and sensitive patients
How Cromolyn Sodium Works
Cromolyn Sodium stabilizes mast cell membranes, preventing the release of histamine, prostaglandins, and leukotrienes that trigger allergic and inflammatory responses. With minimal absorption into the bloodstream, it delivers a strong safety profile and reliable long-term symptom control for patients managing mast cell disorders.
Supplements to Support Ketotifen & Cromolyn Therapy
Our pharmacists recommend targeted supplements to complement mast cell stabilizer therapy, helping optimize symptom control, immune balance, and overall well-being.
- Vitamin D3 5,000 IU + K2 – promotes immune balance, bone health & calcium regulation
- Reacted Zinc – supports immune resilience & skin integrity
- Orthomega® 820 – delivers EPA/DHA omega-3s for anti-inflammatory & cardiovascular benefits
- Ortho Biotic Capsules – provides probiotics & prebiotics to support gut & immune health
These supplements are supportive additions and do not replace prescription therapy. Ask our pharmacists if adjunctive supplementation is appropriate for your care plan.
Storage & Safety Information for Compounded Ketotifen & Cromolyn Sodium
Storage Guidelines
Store compounded Ketotifen and Cromolyn Sodium at controlled room temperature 68°F–77°F (20°C–25°C), unless otherwise directed by your pharmacist.
Keep medications in their original, tightly sealed containers, away from sunlight, heat, and humidity. Some liquid formulations may require refrigeration — always check your prescription label.
For questions about storage, expiration, or shelf life, call (201) 444-4190 or email info@rockridgepharmacy.com.
Potential Side Effects
Compounded Ketotifen may cause drowsiness, mild sedation (especially when starting therapy), dry mouth, occasional weight gain, or stomach upset. Compounded Cromolyn Sodium is generally well tolerated but may cause mild headache, gastrointestinal upset, throat irritation (with oral liquids), or rarely a skin rash.
Note: Most side effects are mild and temporary as the body adjusts. Report persistent or severe symptoms to your healthcare provider. Always consult your provider before starting, changing, or stopping treatment with compounded mast cell stabilizers.
Cost of Compounded Ketotifen & Cromolyn Sodium
Pricing varies based on formulation (capsules or trigger-free liquid), dosage strength, and the level of customization. Each prescription is prepared in our USP <795>/<800>-compliant lab using pharmaceutical-grade ingredients for safety, purity, and effectiveness.
These mast cell stabilizers are commonly prescribed for Mast Cell Activation Syndrome (MCAS), mastocytosis, and Hereditary Alpha Tryptasemia (HAT). Our pharmacists work closely with your provider to ensure dosing and formulation match your exact needs.
For details on custom pricing, please call Rock Ridge Pharmacy at (201) 444-4190 .
Why Rock Ridge Pharmacy for Compounded Ketotifen & Cromolyn?
- Customized formulations — capsules or trigger-free liquids tailored for MCAS, mastocytosis, and allergic GI conditions.
- USP <795> & <800> compliant lab — strict safety standards ensure purity, stability, and accurate dosing.
- Collaborative pharmacist support — direct provider communication, education, and adjustments to improve symptom control.
Our pharmacists oversee every stage of compounding — from ingredient sourcing to dosing accuracy. Each prescription is carefully reviewed to match your provider’s treatment plan.
Patients benefit from personalized guidance on dosing, safety, and therapy monitoring, ensuring compounded Ketotifen and Cromolyn are safe, effective, and well-tolerated.
FAQS About Compounded Ketotifen & Cromolyn Sodium at Rock Ridge Pharmacy
What is compounded Ketotifen used for?
Compounded Ketotifen is a dual-action mast cell stabilizer and H₁ antihistamine used to manage Mast Cell Activation Syndrome (MCAS), mastocytosis, and other allergic or inflammatory conditions. It reduces histamine release and controls symptoms such as itching, hives, and swelling.
What is compounded Cromolyn Sodium used for?
Compounded Cromolyn Sodium is a non-sedating mast cell stabilizer often prescribed for MCAS, mastocytosis, and allergic gastrointestinal disorders. It prevents the release of inflammatory mediators, making it a preferred long-term treatment option for sensitive patients.
Why choose compounded formulations over commercial products?
Commercial options may contain dyes, additives, or sweeteners that can trigger symptoms in mast cell patients. Compounding allows for customized strengths and trigger-free formulations tailored to your provider’s specifications.
What dosage forms are available at Rock Ridge Pharmacy?
We offer compounded Ketotifen in capsules (commonly 0.5 mg, 1 mg, and 2 mg, with custom strengths available) and alcohol-free, dye-free liquid suspensions for sensitive patients. Compounded Cromolyn Sodium is available in 100 mg and 200 mg capsules, with custom strengths, and in a trigger-free, alcohol-free liquid formulation.
Are compounded Ketotifen and Cromolyn Sodium safe for long-term use?
Yes—both are generally well-tolerated when prescribed by your provider. Cromolyn Sodium has minimal systemic absorption, and Ketotifen has a long history of safe use in mast cell disorders. Pharmacist monitoring ensures ongoing safety.
How long does it take for Ketotifen or Cromolyn Sodium to work?
Timelines vary. Some patients notice symptom relief in days, while others require several weeks of consistent use—particularly with Cromolyn Sodium, which works best with regular dosing.
Do these medications cause drowsiness?
Ketotifen may cause mild sedation, especially when first starting treatment. Cromolyn Sodium is non-sedating and does not typically affect alertness.
Can Ketotifen or Cromolyn Sodium be taken with other medications?
Yes, but potential drug interactions should always be reviewed. Inform your provider and pharmacist about all medications, supplements, and over-the-counter products you take.
How should I store Ketotifen and Cromolyn Sodium?
Store at controlled room temperature (68°F–77°F), away from heat, light, and moisture. Some liquid formulations may require refrigeration—check your prescription label for instructions.
Can children take compounded Ketotifen or Cromolyn Sodium?
Yes—if prescribed by a pediatrician. Compounding allows for child-friendly strengths and alcohol-free liquids, ensuring safer dosing for pediatric patients.
Are compounded mast cell stabilizers safe for sensitive patients?
Yes. Compounding removes dyes, fillers, and additives that often trigger reactions in mast cell patients, providing a purer formulation tailored to individual sensitivities.
Do I need a prescription for compounded Ketotifen or Cromolyn Sodium?
Yes—a valid prescription from a licensed healthcare provider is required. Compounded medications are made specifically for your needs and are not available over the counter.
How can my provider send a prescription to Rock Ridge Pharmacy?
Providers can e-scribe to “Rock Ridge Pharmacy,” fax to 201-444-2698, or call 201-444-4190. They may also email info@rockridgepharmacy.com for assistance.
How much do compounded Ketotifen and Cromolyn Sodium cost?
Pricing depends on strength, dosage form, and customization. Contact us at 201-444-4190 or info@rockridgepharmacy.com for a personalized quote.
How can I contact Rock Ridge Pharmacy for more information?
Call 201-444-4190, email info@rockridgepharmacy.com, or visit our Contact Us page for more information.
Ways to Send In Prescriptions for Compounded Ketotifen and Cromolyn
1. Fax
Write a prescription on a prescription pad and fax over to 201-444-2698
We'll take care of the rest!
2. E-Scribe
E-Rx (E-scribe) to “Rock Ridge Pharmacy”
Make sure our address is 191 Rock Rd, Glen Rock, NJ 07452.
3. Call
- Call in your prescription to
- 201-444-4190.
We want to make sure it's as easy as possible for our patients!
4. Telemedicine
Rock Ridge Pharmacy, in partnership with Physician 360 offers convenient on-demand telemedicine consultations