Compounded Formula • Prescription Required
All-Purpose Nipple Ointment (APNO)
Rock Ridge Pharmacy offers custom-compounded All-Purpose Nipple Ointment (APNO) to help nursing mothers relieve nipple pain, irritation, and inflammation while supporting the breastfeeding journey.
All-Purpose Nipple Ointment (APNO)
All-Purpose Nipple Ointment (APNO) is a specially compounded medication designed to provide relief for breastfeeding mothers dealing with sore nipples and related discomforts.
This unique formulation combines three key components: an antibiotic, an anti-inflammatory, and an antifungal agent. APNO helps prevent and treat bacterial and fungal infections, especially in cases of severely damaged nipples.
Breastfeeding mothers rely on APNO for its proven ability to promote healing, reduce pain, and support a more comfortable breastfeeding journey. At Rock Ridge Pharmacy, each prescription is compounded in our USP <795> / <800> compliant lab with the highest standards of quality and care.

How Does All-Purpose Nipple Ointment (APNO) Work?
Antibiotic (Mupirocin 2% Ointment)
Specifically targets and treats bacterial skin infections, creating a protective barrier to prevent further microbial growth. Mupirocin helps heal cracked or damaged nipples caused by breastfeeding, reducing the risk of infection.
Anti-inflammatory (Betamethasone 0.1% Ointment)
Soothes swelling, itching, redness, and irritation, providing relief from inflammation. Betamethasone promotes faster healing and comfort for mothers experiencing sore and inflamed nipples during breastfeeding.
Antifungal (Miconazole 2%)
Effectively combats yeast and fungal infections, including thrush, a common issue for breastfeeding mothers. Miconazole prevents and treats fungal infections, ensuring healthier nipples and a more comfortable breastfeeding experience.
How to Apply All-Purpose Nipple Ointment (APNO)
A simple guide for safe, effective use while supporting a comfortable breastfeeding journey.
Step 1: Apply After Feeding
After each breastfeeding session, apply a small amount of APNO to the nipple and areola. Gently massage to ensure full coverage and absorption.
Step 2: Use Consistently
Apply APNO after every feeding or as directed by your healthcare provider. Regular use helps prevent infections and supports healing of sore or cracked nipples.
Step 3: No Need to Wash Off
APNO is safe for your baby, so there’s no need to wash it off before the next feeding. This makes breastfeeding easier and more convenient.
Step 4: Safe & Effective
When used as directed, APNO is non-toxic and safe for both mother and baby, providing comfort and protection throughout breastfeeding.
Supplements to Support All-Purpose Nipple Ointment (APNO)
Alongside APNO therapy, select supplements can help reduce inflammation, support healing, and strengthen maternal health. Always consult your provider or pharmacist before starting new supplements.

- Vitamin D – supports immune function and maternal recovery
- Omega-3 Fatty Acids – promote anti-inflammatory balance and healing
- Probiotics – maintain a healthy microbiome and reduce yeast overgrowth
- Zinc – aids in tissue repair and skin healing
- Vitamin C – supports collagen production and wound healing
These supplements complement APNO therapy but are not substitutes for prescribed treatment. Consult your Rock Ridge pharmacist for safe use alongside APNO.
Storage & Safety Information for All-Purpose Nipple Ointment (APNO)
Proper use and handling of APNO ensures comfort, safety, and effective relief during breastfeeding.
Storage Guidelines
Store APNO at room temperature (68°F–77°F / 20°C–25°C) in a cool, dry place away from heat, humidity, and direct sunlight. Keep tightly closed in its original, labeled container.
Always store out of reach of children and pets. Do not refrigerate or freeze unless instructed by your pharmacist.
Questions about storage or expiration? Call (201) 444-4190 or email info@rockridgepharmacy.com.
Safety & Use Considerations
APNO is generally safe and well-tolerated when applied as directed. Some mothers may experience:
- Mild Stinging: Temporary sensation after application, usually subsides quickly.
- Skin Irritation: Rare; discontinue use and consult your provider if persistent.
Is APNO Safe for Ongoing Use?
Yes. APNO may be used throughout breastfeeding as directed by your provider. Continuous monitoring ensures optimal comfort and healing.
Disclaimer: This content is for educational purposes only and is not a substitute for medical advice. Always consult your healthcare provider before starting, changing, or discontinuing compounded therapy.
How Quickly Does All-Purpose Nipple Ointment (APNO) Work?
Relief time may vary, but many mothers notice improvement within the first few days of consistent use.

Immediate Soothing
Many women experience reduced stinging and soreness within the first few applications.
Healing Over Time
With consistent use after feedings, healing of cracked or damaged nipples is often seen within 3–7 days.
Key Takeaway
Results vary by severity and consistency. Regular application and follow-up with your provider ensure the best breastfeeding comfort and outcomes.
Cost of All-Purpose Nipple Ointment (APNO)
Custom Compounding: APNO is prepared in our compounding lab using a precise combination of an antibiotic, anti-inflammatory, and antifungal, tailored to your provider’s prescription.
Affordable Relief: Rock Ridge Pharmacy offers APNO at competitive pricing, ensuring effective and safe nipple care remains accessible to breastfeeding mothers.
Pharmacist Oversight: Each prescription is compounded with accuracy and care, with our pharmacists available to guide proper use and answer safety questions.
For details on APNO pricing, please call Rock Ridge Pharmacy at (201) 444-4190 or email info@rockridgepharmacy.com .

Why Rock Ridge Pharmacy for Compounded APNO?
- Custom formulation — includes antibiotic, anti-inflammatory, and antifungal agents as prescribed.
- USP <795> & <800> compliant lab — ensuring safety, precision, and consistency.
- Timely service — most APNO prescriptions ready within 24–48 hours in New Jersey.
Our compounding pharmacists prepare each APNO prescription with care, following strict quality standards and aligning with your provider’s directions for optimal breastfeeding support.
Patients also receive personalized pharmacist guidance — from application instructions to monitoring for skin sensitivity — ensuring safe and effective use throughout the breastfeeding journey.
Frequently Asked Questions (FAQs) about All-Purpose Nipple Ointment (APNO) at Rock Ridge Pharmacy
What is All-Purpose Nipple Ointment (APNO)?
APNO is a compounded ointment designed for breastfeeding mothers. It combines an antibiotic, anti-inflammatory, and antifungal to relieve sore nipples, promote healing, and prevent infections.
What Ingredients Are in APNO?
Typical formulations include Mupirocin 2% (antibiotic), Betamethasone 0.1% (anti-inflammatory), and Miconazole 2% (antifungal). Your provider may adjust based on your needs.
How Do I Apply APNO?
After breastfeeding, apply a thin layer to the nipple and areola. No need to wash off before the next feeding, as APNO is safe for babies. Use consistently after each session unless otherwise directed.
How Quickly Does APNO Work?
Many women feel relief within the first few applications. Healing of cracked or damaged nipples often occurs within 3–7 days of consistent use.
Is APNO Safe for My Baby?
Yes. APNO is applied topically and does not need to be removed before nursing. It is safe and non-toxic when used as directed under medical supervision.
Do I Need a Prescription for APNO?
Yes, APNO requires a prescription. Your healthcare provider can send it via e-prescription, fax, or directly to Rock Ridge Pharmacy.
Can APNO Cause Side Effects?
Side effects are rare but may include mild stinging or skin irritation. If irritation persists, discontinue use and consult your provider.
How Should APNO Be Stored?
Store at room temperature (68°F–77°F), away from heat, moisture, and direct sunlight. Keep out of reach of children and pets.
Can I Speak to a Pharmacist About APNO?
Absolutely! Our pharmacists are available for one-on-one consultations to review application, safety, and any concerns during your breastfeeding journey.
Take Control of Your Health Today
Call (201) 444-4190 or book online today. Our team is ready to support your unique women’s health journey with personalized compounded medications.